Testosterone aromatizes very easily and therefore estrogen buildup and side effects can become an issue for users sensitive to these problems or those choosing to use a high dose of this compound. Therefore, when using Testosterone, bodybuilders often choose in incorporate an anti-estrogen such as Anastrozole, Proviron, Tamoxifen to help keep estrogen related side effects to a minimum. Extremely sensitive users, or users using very high doses (800-1200mgs) might find that stronger anti-estrogens such as Letrozole or Exemestane are more suitable. Androgenic side effects such as oily skin are also possible while taking Testosterone.
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Drugs such as Nolvedex bind to the oestrogen receptors , therefore reducing the effects of the heightened oestrogen in the body. Such drugs do nothing to reduce the amount of oestrogen in the body; they merely reduce its effects via competition for the receptors . If the user wishes to reduce the amount of oestrogen they should look to drugs such as proviron and anastrozole , which are known as anti-aromatases - . they lower the conversion of the steroid to oestrogen and therefore reduces the overall amount of oestrogen present.