There are possible estrogenic side effects of Nandrolone despite it not being a very estrogenic hormone, at least not directly. Nandrolone does aromatize slightly. Aromatization refers to the conversion of testosterone to estrogen . This takes place when the testosterone hormone interacts with the aromatase enzyme. When the conversion takes place this can cause estrogen levels to go up, which can promote gynecomastia and water retention. High blood pressure can also become an issue if water retention becomes severe. Along with the low level of aromatase activity Nandrolone is also a progestin and has a strong binding affinity for the progesterone receptor. This may stimulate the mammary tissue and enhance the risk of gynecomastia in sensitive individuals.
Combating the estrogenic side effects of Nandrolone can be achieved by the use of anti-estrogen medications, specifically Aromatase Inhibitors (AI’s) such as Anastrozole ( Arimidex ). Selective Estrogen Receptor Modulators (SERM’s) are also sometimes used, such as Tamoxifen ( Nolvadex ). However, AI’s are the proper choice as they will directly reduce serum estrogen levels and SERM’s will not. An AI should be enough to reduce and avoid gynecomastia unless the individual already has existing gynecomastia that could potentially be exasperated.
Important Note: It’s often been said that Nandrolone based gynecomastia is based on increases in prolactin. It is true that 19-nor steroids can increase prolactin, which can also negatively affect libido and erection function. Some men may need to use a dopamine agonist to combat this. However, it is not prolactin that causes 19-nor based gynecomastia but rather the imbalance between estrogen and progesterone. If you merely combat prolactin you may find yourself with the very gynecomastia you tried to avoid.
In bodybuilding, Nandrolone undecanoate is often used for mass build-up, as it has a strong anabolic and moderate androgenic effect. Due to the severe impairment of the body’s testosterone production, it is frequently injected with testosterone. Compared to nandrolone decanoate , the price and the need for frequent injections is a crucial drawback. For beginners and women the number of necessary injections is still within the scope. Professional Bodybuilders dont use Nandrolone Undecanoate, since noone wants to make several injections in one day.
For the steroid user, this steroid can almost be called essential to an off-season mass plan. But when we look at what it can do for recovery and healing it is almost in a class of its own. Couple this with its side effect friendly nature and this steroid is very hard to beat. However, there’s one important thing we’ve yet to address, erectile dysfunction. Nandrolone is well known for causing erectile dysfunction, often referred to as “ Deca Dick.” This isn’t the hormone’s fault; it is due to improper use. As a progestin and a hormone that can produce prolactin erection function can be diminished. Keep a balance in your hormone levels and there won’t be an issue.