Like other AAS, drostanolone is an agonist of the androgen receptor (AR).  It is not a substrate for 5α-reductase and is a poor substrate for 3α-hydroxysteroid dehydrogenase (3α-HSD), and therefore shows a high ratio of anabolic to androgenic activity.  As a DHT derivative, drostanolone is not a substrate for aromatase and hence cannot be aromatized into estrogenic metabolites .  While no data are available on the progestogenic activity of drostanolone, it is thought to have low or no such activity similarly to other DHT derivatives.  Since the drug is not 17α-alkylated , it is not known to cause hepatotoxicity . 
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Summary: While clearly a powerful anabolic steroid with amazing anti-estrogenic properties, Masteron overdose must be avoided in all circumstances. Like many other steroids, it is not suitable for use by anyone with a prevailing health condition. For the rest of the people though, it is an amazing transformation agent that can help you quickly realize your goals of a stronger body with more muscle density. Its anti-estrogenic properties are essential in taking care of most of the side-effects experienced by use of anabolic steroids, such as high blood pressure and water retention. Post cycle therapy is also essential after the use of Masteron. Depending on your goals, you may choose to stack Masteron with other products to achieve optimal results. The product is highly toxic and dangerous. We advice against using it.