Despite all positive effects of doping on the body they could be dangerous. Possible side effects of anabolic steroids can be avoided by choosing the right form (oral or injectable) and combination as well as by taking reasonable androgenic dosages. It has to be mentioned, that the most side effects of drugs disappear after the cycle is completed. Moreover, many of them can be blocked during the cycle by using respective supplements. Therefore, in order to avoid possible negative consequences one shall pay attention to studying information about the drugs prior to use them.
Typically, any athlete who tests positive for banned substances after having served a previous ban receives a lifetime ban from the sport of athletics. Many high-profile sportspeople to receive doping bans have come from the sport of athletics, with significant past cases concerning Ben Johnson , Marion Jones and Tim Montgomery . Furthermore, a number of athletes who underwent state-sponsored doping programmes in East Germany between the 1960s and 1980s were competitors in athletics, but the quality of the international anti-doping work was so poor that only one East German athlete ever tested positive.  Following allegations of state-sponsored doping in Russia , the IAAF suspended the country's athletes from competition, including the 2016 Summer Olympics.
Like other AAS, drostanolone is an agonist of the androgen receptor (AR).  It is not a substrate for 5α-reductase and is a poor substrate for 3α-hydroxysteroid dehydrogenase (3α-HSD), and therefore shows a high ratio of anabolic to androgenic activity.  As a DHT derivative, drostanolone is not a substrate for aromatase and hence cannot be aromatized into estrogenic metabolites .  While no data are available on the progestogenic activity of drostanolone, it is thought to have low or no such activity similarly to other DHT derivatives.  Since the drug is not 17α-alkylated , it is not known to cause hepatotoxicity .